Ipsilateral recurrent breast cancer

Ipsilateral recurrent breast cancer

– The seventh Dutch Snapshot study –

PARTICIPATING CENTERS

18th of September 2020

Rationale

The risk of ipsilateral recurrent breast cancer (IBTR) after breast-conserving treatment (BCT) is approximately 0,5- 1% per year. The gold standard for IBTR has always been salvage mastectomy. However, there is increasing interest in repeat BCT options in selected patients with IBTR. We would like to assess the current clinical practice in The Netherlands.

STUDY DESIGN

The IBTR SNAPSHOT is a nationwide retrospective multicenter registration study. A PALGA search yielded approximately 1500 patients diagnosed with IBTR in 2016 and 2017. Local pathology labs can provide patient identification numbers matching these pathology reports to a local breast surgeon, resident or fellow. Anonimized data gathering is performed via electronic case report forms via ResearchManager.

OBJECTIVE

To evaluate the clinical practice in The Netherlands regarding surgical management of locally recurrent breast cancer after previous breast-conserving therapy in 2016 and 2017.

STUDY POPULATION

Women with IBTR after previous BCT, diagnosed with IBTR in 2016 and 2017

Outcomes

Primary endpoint is the incidence of repeat BCT and salvage mastectomy in the Netherlands. Secondary endpoints are local and systemic (neo)adjuvant treatment regimens for locally recurrent breast cancer and the postoperative complications of both repeat BCT and salvage mastectomy.

Other projects

Six other projects are performed by the Dutch Snapshot Research Group

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